PHARMACEUTICAL STUDY AND ANALYTICAL STANDARDIZATION OF SUTABHASMA YOGA: A AYURVEDIC CLASSICAL HERBO-MINERAL FORMULATION

Mahantesh Pujeri*, Kasinath Hadimur, K. A. Patil

Introduction: Sutabhasma Yoga is a classical herbo-mineral formulation described in Rasendra Sara Sangraha for the management of Apasmara. The therapeutic efficacy, safety and quality of herbomineral formulations depend on proper pharmaceutical processing and analytical standardization. Scientific documentation of the pharmaceutical procedures and physicochemical characteristics is essential to establish quality control parameters and ensure reproducibility of classical Ayurvedic formulations. Materials and Methods: sutabhasma Yoga was prepared according to the classical procedures described in Rasendra Sara Sangraha. The pharmaceutical process included Parada Shodana, Gandhaka Shodana, Kajjali Nirmana, Navasadara Shodana, Bhavana with Nimbu swarasa, preparation of Rasasindura, Medya Kashaya Bhavana to obtain Sutabhasma Yoga. The finished formulation was subjected to organoleptic evaluation and physicochemical analysis including solubility, moisture content, total Ash value, pH and specific gravity using standard analytical procedures. Results: The final product was obtained as a reddish-brown, odourless, tasteless, smooth fine powder. Physicochemical evaluation showed that the formation was insoluble in distilled water, methanol, ethanol, xylene, chloroform, hydrochloric acid and sulphuric acid. The moisture content was 3.45, Total Ash value 58.25, pH 8.0 and specific gravity 1.004, indicating satisfactory physicochemical characteristics. Discussion: The sequential pharmaceutical procedures ensured proper purification and processing of the ingredients, resulting in a stable herbomineral formulation. The low moisture content suggests adequate drying and better storage stability, while the high ash value reflects the presence of processed mineral constituents. The mildly alkaline ph and consistent organoleptic characteristics further support the quality and uniformity of the prepared formulation. These findings provide preliminary quality control standards for Sutabhasma Yoga. Conclusion: Sutabhasma Yoga was successfully prepared following the classical pharmaceutical procedures. The pharmaceutical observation and physicochemical evaluation established quality control parameters that may serve as reference standards for the standardization and scientific validation of this classical herbomineral formulation.